BREEDING SERVICES
Back
J:NU
Strain number : 007850
Common Name: COutbred Athymic Nude Mice
- It is an outbred strain.
- Outbred homozygous nude (Foxn1nu/Foxn1nu) mice are the standard in vivo model for drug efficacy testing in oncology.
- Nude mice are athymic and hairless as a result of the recessive “nu” mutation.
- Although T cell precursors exist, their development is blocked because of the absence of a thymus, resulting in an immunodeficiency that permits transplantation of tumour cell xenografts hence, these outbred nude mice act as immunodeficient tumour transplant hosts.
- Homozygous females are poor breeders and fail to lactate.
- Heterozygous males and females breed well and have normal immune function.
- Homozygous pups can be identified at as young as 24 hours by their lack of whiskers or poorly developed, crinkled whiskers.
Body Weight Information
For more detailed information please visit
