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BALB/cJ
Strain number : 000651
Common Name: BALBc mice, BALB/c mice
- BALB/cJ is a commonly used inbred sub strain.
- BALB/c mice are well known for the production of plasmacytomas following injection with mineral oil forming the basis for the production of monoclonal antibodies.
- Key traits include susceptibility to developing the demyelinating disease upon infection with Theiler's murine encephalomyelitis virus.
- Rare spontaneous myoepitheliomas arising from myoepithelial cells of various exocrine glands have been observed in this sub strain.
- BALB/c mice develop other cancers later in life including reticular neoplasms, primary lung tumors, and renal tumors.
- The BALB/cJ sub strain is susceptible to Listeria, all species of Leishmania, and several species of Trypanosoma, but is resistant to experimental allergic orchitis (EAO).
Body Weight Information
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